Recombinant Human TIA1 Protein, MYC/DDK-tagged

• Cat.No.: TIA1-1047H
• Product Overview: Recombinant human TIA1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 42.8 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TIA1 TIA1 cytotoxic granule-associated RNA binding protein [ Homo sapiens ]
• Official Symbol: TIA1
• Synonyms: TIA-1; WDM
• Gene ID: 7072
• mRNA Refseq: NM_022037
• Protein Refseq: NP_071320
• MIM: 603518
• UniProt ID: P31483