Recombinant Human Thymic Stromal Lymphopoietin, Fc Chimera

• Cat.No.: TSLP-2147H
• Product Overview: Recombinant human mature TSLP(C-terminus fused with murine IgG1 Fc)produced inmammalian cells contains 358 amino acids with predicted molecular weight 40.31KD x 2 (dimer). It contains 13 cysteine and 3 N-link glycosylation sites with increased MW up to 15 KD x2 (dimer).

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Description: A recent publication in Nature Immunology demonstrated that human TSLP functions very differently from murine TSLP and plays an important role in regulating TH1 an dTH2 development in dendritic cells. No antibodies are commercially available to characterize its immunoreactivity.
• Purity: >90%.
• Recommended Storage Temperature: -70 °C.

Gene Information

• Gene Name: TSLP thymic stromal lymphopoietin [ Homo sapiens ]
• Synonyms: Thymic Stromal Lymphopoietin; Thymic stromal lymphopoietin Precursor; TSLP
• Gene ID: 85480
• mRNA Refseq: NM_033035
• Protein Refseq: NP_149024
• MIM: 607003
• UniProt ID: Q969D9
• Chromosome Location: 5q22.1
• Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
• Function: cytokine activity