Recombinant Human TGIF2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TGIF2-2401H
• Product Overview: TGIF2 MS Standard C13 and N15-labeled recombinant protein (NP_068581) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 25.9 kDa
• AA Sequence: MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSVLAVSVPAPTNVLSLSVCSMPLHSGQGEKPAAPFPRGELESPKPLVTPGSTLTLLTRAEAGSPTGGLFNTPPPTPPEQDKEDFSSFQLLVEVALQRAAEMELQKQQDPSLPLLHTPIPLVSENPQTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TGIF2 TGFB-induced factor homeobox 2 [ Homo sapiens (human) ]
• Official Symbol: TGIF2
• Synonyms: TGIF2; TGFB-induced factor homeobox 2; TGFB induced factor 2 (TALE family homeobox); homeobox protein TGIF2; 5-TG-3 interacting factor 2; TGF-beta-induced transcription factor 2; TGF(beta)-induced transcription factor 2; TGFB-induced factor 2 (TALE family homeobox); transcription growth factor-beta-induced factor 2
• Gene ID: 60436
• mRNA Refseq: NM_021809
• Protein Refseq: NP_068581
• MIM: 607294
• UniProt ID: Q9GZN2