Recombinant Human TG Protein

• Cat.No.: TG-0056H
• Product Overview: Recombinant Human TG Protein without tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Description: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
• Applications: ELISA, CLIA, CG
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Short term (up to 7 days) store at 2–8 centigrade. Long term, store at - 20 centigrade. Avoid multiple freeze/thaw cycles.
• Storage Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH7.4

Gene Information

• Gene Name: TG thyroglobulin [ Homo sapiens (human) ]
• Official Symbol: TG
• Synonyms: TG; thyroglobulin; AITD3; TGN
• Gene ID: 7038
• mRNA Refseq: NM_003235
• Protein Refseq: NP_003226
• MIM: 188450
• UniProt ID: P01266