Recombinant Human TCEB3 cell lysate

• Cat.No.: TCEB3-1751HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) [ Homo sapiens ]
• Official Symbol: TCEB3
• Synonyms: TCEB3; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B (SIII), polypeptide 3 (110kD, elongin A); transcription elongation factor B polypeptide 3; SIII; TCEB3A; elongin-A; elongin 110 kDa subunit; transcription elongation factor B alpha subunit; RNA polymerase II transcription factor SIII subunit A1; EloA; SIII p110; FLJ38760; FLJ42849
• Gene ID: 6924
• mRNA Refseq: NM_003198
• Protein Refseq: NP_003189
• MIM: 600786
• UniProt ID: Q14241
• Chromosome Location: 1p36.1
• Pathway: Disease, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; Gene Expression, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem
• Function: DNA binding