Recombinant Human TCEA2, His-tagged

• Cat.No.: TCEA2-7621H
• Product Overview: Recombinant human TCEA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: Non
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.25M NaCl
• Molecular Mass: 36kDa (322aa)
• Protein length: 1-299aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMGKEEE IARIARRLDK MVTKKSAEGA MDLLRELKAM PITLHLLQST RVGMSVNALR KQSSDEEVIA LAKSLIKSWK KLLDASDAKA RERGRGMPLP TSSRDASEAP DPSRKRPELP RAPSTPRITT FPPVPVTCDA VRNKCREMLT AALQTDHDHV AIGADCERLS AQIEECIFRD VGNTDMKYKN RVRSRISNLK DAKNPDLRRN VLCGAITPQQ IAVMTSEEMA SDELKEIRKA MTKEAIREHQ MARTGGTQTD LFTCGKCRKK NCTYTQVQTR SSDEPMTTFV VCNECGNRWK FC
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml?

Gene Information

• Gene Name: TCEA2 transcription elongation factor A (SII), 2 [ Homo sapiens ]
• Official Symbol: TCEA2
• Synonyms: TCEA2; transcription elongation factor A (SII), 2; transcription elongation factor A protein 2; TFIIS; testis-specific S-II; transcription elongation factor TFIIS.1; transcription elongation factor TFIIS.l; transcription elongation factor S-II protein 2
• Gene ID: 6919
• mRNA Refseq: NM_003195
• Protein Refseq: NP_003186
• MIM: 604784
• UniProt ID: Q15560
• Chromosome Location: 20q13.33
• Function: DNA binding; metal ion binding; protein binding; translation elongation factor activity; zinc ion binding