TCEA2
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Official Full Name
transcription elongation factor A (SII), 2 -
Overview
The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TCEA2;transcription elongation factor A (SII), 2;transcription elongation factor A protein 2;TFIIS;Testis specific S II;Transcription elongation factor A (SII) 2;Transcription elongation factor A 2;Transcription elongation factor S II protein 2;Transcription elongation factor TFIIS.l;testis-specific S-II;transcription elongation factor TFIIS.1;transcription elongation factor S-II protein 2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E. coli
- HEK293T
- His
- His&T7
- Non
- Myc&DDK
- His&SUMO
- His&Fc&Avi
Involved Pathway
TCEA2 involved in several pathways and played different roles in them. We selected most pathways TCEA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TCEA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TCEA2 has several biochemical functions, for example, DNA binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TCEA2 itself. We selected most functions TCEA2 had, and list some proteins which have the same functions with TCEA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ADH1C,ZCCHC17,ZFAND5,TAB2,RECQL4,DNPEP,SYVN1,DNMT1,USP49,RBCK1 |
| protein binding | PDIA2,EIF3H,COL6A5,EIF3D,KIF3A,HINT2,CCDC151,TUBA4A,TTBK2,TMEM242 |
| DNA binding | ZNF358,TFIP11,MB21D2,GM239,TAF6L,ZNF556,RCOR1,CEBPG,NKX3.3,MIER1B |
Interacting Protein
TCEA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TCEA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TCEA2.
TRAF2;TNIP1;MEOX2;DAB1;ALAS1;TRIM27
Resources
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References
- Macovei, A; Balestrazzi, A; et al. The TFIIS and TFIIS-like genes from Medicago truncatula are involved in oxidative stress response. GENE 470:20-30(2011).
- Kim, J; Guermah, M; et al. RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells. CELL 137:459-471(2009).
