Recombinant Human TBR1, His-tagged

• Cat.No.: TBR1-29457TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1-626 of Human TBR1 with an N terminal His tag; Predicted MWt 69 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 1-626 a.a.
• Description: This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 163 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Store at 4°C. Upon reconstitution store at -80oC.
• Sequences of amino acids: MQLEHCLSPSIMLSKKFLNVSSSYPHSGGSELVLHDHPII STTDNLERSSPLKKITRGMTNQSDTDNFPDSKDSPGDV QRSKLSPVLDGVSELRHSFDGSAADRYLLSQSSQPQSA ATAPSAMFPYPGQHGPAHPAFSIGSPSRYMAHHPVITN GAYNSLLSNSSPQGYPTAGYPYPQQYGHSYQGAPFYQFSS TQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRR MFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQGGK WVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGK LKLTNNKGASNNNGQMVVLQSLHKYQPRLHVVEVNEDG TEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNP FAKGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGAR YAMAGSFLQDQFVSNYAKARFHPGAGAGPGPGTDRSVP HTNGLLSPQQAEDPGAPSPQRWFVTPANNRLDFAASAY DTATDFAGNAATLLSYAAAGVKALPLQAAGCTGRPLGYYADPSGWGARSPPQYCGTKSGSVLPCWPNSAAAAARMAGA NPYLGEEAEGLAAERSPLPPGAAEDAKPKDLSDSSWIE TPSSIKSIDS

Gene Information

• Gene Name: TBR1 T-box, brain, 1 [ Homo sapiens ]
• Official Symbol: TBR1
• Synonyms: TBR1; T-box, brain, 1; T-box brain protein 1
• Gene ID: 10716
• mRNA Refseq: NM_006593
• Protein Refseq: NP_006584
• MIM: 604616
• Uniprot ID: Q16650
• Chromosome Location: 2q24.2
• Function: DNA binding; sequence-specific DNA binding transcription factor activity