TBR1
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Official Full Name
T-box, brain, 1 -
Overview
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. -
Synonyms
TBR1;T-box, brain, 1;T-box brain protein 1;T-brain-1;TBR-1;TES-56;MGC141978
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBR1-16520M | Recombinant Mouse TBR1 Protein | Mammalian Cells | Mouse | His |
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| TBR1-29457TH | Recombinant Human TBR1, His-tagged | E.coli | Human | His | 1-626 a.a. |
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| TBR1-1207HCL | Recombinant Human TBR1 293 Cell Lysate | HEK293 | Human | Non |
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| TBR1-9054M | Recombinant Mouse TBR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TBR1-9054M-B | Recombinant Mouse TBR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TBR1 involved in several pathways and played different roles in them. We selected most pathways TBR1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TBR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TBR1 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBR1 itself. We selected most functions TBR1 had, and list some proteins which have the same functions with TBR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | ZNF565,TBX5B,RCAN1,TRIM22,PRDM15,IRF2A,STAT2,PRRX2,HOXB3A,DEAF1 |
| RNA polymerase II core promoter sequence-specific DNA binding | MITF,ZNF335,GATA3,WBP2,SOX3,ZFP335,SOX11,STAT6,NR4A2,TP53 |
Interacting Protein
TBR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBR1.
RFXANK;IKBKE;CASK;ESR1
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