Recombinant Human TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, His-tagged

• Cat.No.: TBC1D1-329H
• Product Overview: TBC1D1, 1-265aa, Human, His tag, E.coli

Specification

• Description: TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, also known as TBC1D1, may act as a GTPase-activating protein for Rab family protein(s). This protein may play a role in the cell cycle and differentiation of various tissues. This protein is involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells. Recombinant human TBC1D1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 33.2 kDa (288aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEEEAF KMLKFLMFDM GLRKQYRPDM IILQIQMYQL SRLLHDYHRD LYNHLEEHEI GPSLYAAPWF LTMFASQFPL GFVARVFDMI FLQGTEVIFK VALSLLGSHK PLILQHENLE TIVDFIKSTL PNLGLVQMEK TINQVFEMDI AKQLQAYEVE YHVLQEELID SSPLSDNQRM DKLEKTNSSL RKQNLDLLEQ LQVANGRIQS LEATIEKLLS SESKLKQAML TLELERSALL QTVEELRRRS AEPSDREPEC TQPEPTGD
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)
• Protein length: 1-265 a.a.

Gene Information

• Gene Name: TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 [ Homo sapiens ]
• Official Symbol: TBC1D1
• Synonyms: TBC1D1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; KIAA1108; TBC; TBC1
• Gene ID: 23216
• mRNA Refseq: NM_001253912
• Protein Refseq: NP_001240841
• MIM: 609850
• UniProt ID: Q86TI0
• Chromosome Location: 4p14
• Function: GTPase activator activity; Rab GTPase activator activity