Recombinant Human TANGO2 Protein, His tagged

• Cat.No.: TANGO2-23H
• Product Overview: Recombinant Human TANGO2 Protein with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene belongs to the transport and Golgi organization family, whose members are predicted to play roles in secretory protein loading in the endoplasmic reticulum. Depletion of this gene in Drosophila S2 cells causes fusion of the Golgi with the ER. In mouse tissue culture cells, this protein co-localizes with a mitochondrially targeted mCherry protein and displays very low levels of co-localization with Golgi and peroxisomes. Allelic variants of this gene are associated with rhabdomyolysis, metabolic crises with encephalopathy, and cardiac arrhythmia.
• Molecular Mass: The protein has a calculated MW of 31 kDa.
• AA Sequence: MCIIFFKFDPRPVSKNAYRLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEEGKEGGTWLGISTRGKLAALTNYLQPQLDWQARGRGELVTHFLTTDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGDVICYYGNRGEPDPIVLTPGTYGLSNALLETPWRKLCFGKQLFLEAVERSQALPKDVLIASLLDVLNNEEAQLPDPAIEDQGGEYVQPMLSKYAAVCVRCPGYGTRTNTIILVDADGHVTFTERSMMDKDLSHWETRTYEFTLQSHHHHHH
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile 50 mM Tris, 300 mM NaCl, pH 8.0
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 1.3 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: TANGO2 transport and golgi organization 2 homolog [ Homo sapiens (human) ]
• Official Symbol: TANGO2
• Synonyms: TANGO2; transport and golgi organization 2 homolog; MECRCN; C22orf25; transport and Golgi organization protein 2 homolog
• Gene ID: 128989
• mRNA Refseq: NM_152906
• Protein Refseq: NP_690870
• MIM: 616830
• UniProt ID: Q6ICL3