Recombinant Human TAC1, His-tagged

• Cat.No.: TAC1-7097H
• Product Overview: Recombinant human TAC1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 20-129aa
• Description: TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal sequences that convey receptor specificities. TAC1 is thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. It is known to induce behavioral responses and function as vasodilators and secretagogues.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 2M Urea
• Molecular Mass: 15.6 kDa (135aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMEEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALLKALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: TAC1 tachykinin, precursor 1 [ Homo sapiens ]
• Official Symbol: TAC1
• Synonyms: TAC1; tachykinin, precursor 1; NKNA, TAC2, tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma); protachykinin-1; neurokinin 1; neurokinin 2; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; NPK; substance K; substance P; PPT; neurokinin A; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma); NK2; NKNA; TAC2; Hs.2563
• Gene ID: 6863
• mRNA Refseq: NM_003182
• Protein Refseq: NP_003173
• MIM: 162320
• UniProt ID: P20366
• Chromosome Location: 7q21-q22
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem
• Function: substance P receptor binding