Recombinant Human synuclein, alpha Protein, Tag Free, Biotin Labeled

• Cat.No.: SNCA-034H
• Product Overview: Recombinant human α-synuclein (GenBank Accession # NP_000336) was expressed and purified from E. coli and conjugated with biotin.

Specification

• Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
• Source: E. coli
• Species: Human
• Tag: Non
• Protein length: 1-140aa
• Conjugation/Label: Biotin
• Form: Solution
• Applications: Aggregation/Fibrillation; ELISA; Western Blotting
• Usage: Research use
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 1 mg/mL
• Storage Buffer: 10 mM sodium phosphate buffer (pH=7.4)

Gene Information

• Gene Name: SNCA synuclein, alpha (non A4 component of amyloid precursor) [ Homo sapiens (human) ]
• Official Symbol: SNCA
• Synonyms: SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC110988
• Gene ID: 6622
• mRNA Refseq: NM_000345
• Protein Refseq: NP_000336
• MIM: 163890
• UniProt ID: P37840