Recombinant Human SULT1E1, His-tagged

• Cat.No.: SULT1E1-28402TH
• Product Overview: Recombinant full length human Estrogen Sulfotransferase fused to His tag at C-terminus; amino acids 1-294 , 36.1kDa.

Specification

• Description: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Liver, intestine and at lower level in the kidney.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSLPEFVEK FMQGQVPYGS WYKHVKSWWE KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSFQE MKNNPSTNYT TLPDEIMNQK LSPFMRKGIT GDWKNHFTVA LNEKFDKHYE QQMKESTLKF RTEILEHHHH HH
• Sequence Similarities: Belongs to the sulfotransferase 1 family.
• Protein length: 1-294 a.a.
• Full Length: Full L.

Gene Information

• Gene Name: SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 [ Homo sapiens ]
• Official Symbol: SULT1E1
• Synonyms: SULT1E1; sulfotransferase family 1E, estrogen-preferring, member 1; STE, sulfotransferase, estrogen preferring; estrogen sulfotransferase; EST
• Gene ID: 6783
• mRNA Refseq: NM_005420
• Protein Refseq: NP_005411
• MIM: 600043
• Uniprot ID: P49888
• Chromosome Location: 4q13.1
• Pathway: Biological oxidations, organism-specific biosystem; Cytosolic sulfonation of small molecules, organism-specific biosystem; Metabolism, organism-specific biosystem; Phase II conjugation, organism-specific biosystem; Steroid hormone biosynthesis, organism-specific biosystem
• Function: estrone sulfotransferase activity; flavonol 3-sulfotransferase activity; steroid binding; steroid sulfotransferase activity; transferase activity