Recombinant Human Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1, His-tagged

• Cat.No.: SULT2A1-1782H
• Product Overview: Recombinant humanSULT2A1 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Cat. No.: SULT2A1-1782H
• Description: SULT2A1, also knowndehydroepiandrosterone sulphotransferase, belongs to the sulfotransferasefamily. This protein is mainly expressed in liver and adrenal tissues, and toa lesser extent in kidney. It catalyzes the 3"-phosphoadenosine5"-phosphosulfate-dependent sulfation of a wide variety of steroids in humanliver and adrenal tissues, and is also responsible for most of the sulfationof bile acids in human liver.
• Concentration: 1.0 mg/ml
• Source: Human
• Host: E.coli
• Form: Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1MNaCl and 1mM DTT.
• Purity: > 95% by SDS -PAGE
• Sequence: 1-285 amino acids:MGSSHHHHHH SSGLVPRGSH MSDDFLWFEG IAFPTMGFRS ETLRKVRDEF VIRDEDVIIL TYPKSGTNWLAEILCLMHSK GDAKWIQSVP IWERSPWVES EIGYTALSET ESPRLFSSHL PIQLFPKSFF SSKAKVIYLMRNPRDVLVSG YFFWKNMKFI KKPKSWEEYF EWFCQGTVLY GSWFDHIHGW MPMREEKNFL LLSYEELKQDTGRTI
• Molecular Mass: 35.9 kDa(305aa), confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: SULT2A1

Gene Information

• Gene Name: SULT2A1 sulfotransferase family,cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 [ Homosapiens ]
• Synonyms: SULT2A1; sulfotransferase family, cytosolic, 2A,dehydroepiandrosterone (DHEA)-preferring, member 1; HST; ST2; STD; hSTa;DHEAS; ST2A1; ST2A3; DHEA-ST; bile salt sulfotransferase; bile-saltsulfotranasferase 2A1; alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotransferase; Dehydroepiandrosterone sulfotransferase; HydroxysteroidSulfotransferase; Sulfotransferase 2A1; EC 2.8.2.14;OTTHUMP00000222076
• Gene ID: 6822
• mRNA Refseq: NM_003167
• Protein Refseq: NP_003158
• MIM: 125263
• UniProt ID: Q06520
• Chromosome Location: 19q13.3
• Pathway: Bile secretion; Biologicaloxidations; Cytosolic sulfonation of small molecules; E2F transcriptionfactor network; Fatty acid; Metabolism of lipids and lipoproteins; Metabolismof xenobiotics by cytochrome P450; Phase II conjugation; Regulation of LipidMetabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
• Function: bile-salt sulfotransferaseactivity; sulfotransferase activity; transferase activity