Active Recombinant Human SULT2A1 Protein

• Cat.No.: SULT2A1-92H
• Product Overview: Recombinant human SULT2A1 protein without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.
• Bio-activity: SULT Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride, 10 mM dithiothreitol and 20 μM PAPS)
  Substrate: 17β-estradiol (3-sulfate formation)
  Linear with time up to: 12 min(Determined at 1 μM substrate, using a protein concentration of 12.5 μg/ml)
  Linear with protein up to: 60 μg/ml(Determined at 1 μM substrate, using an incubation time of 5 min)
  Vmax: 1.1 nmol/min/mg protein
  Km: 2.4 μM
• Usage: For laboratory (research) purposes only
• Storage: Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice.
• Concentration: Protein Concentration: 10 mg/ml
• Storage Buffer: 10 mM sodium phosphate (pH 7.4), 140 mM NaCl

Gene Information

• Gene Name: SULT2A1 sulfotransferase family 2A member 1 [ Homo sapiens (human) ]
• Official Symbol: SULT2A1
• Synonyms: SULT2A1; sulfotransferase family 2A member 1; HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST; bile salt sulfotransferase; alcohol/hydroxysteroid sulfotransferase; bile-salt sulfotranasferase 2A1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
• Gene ID: 6822
• mRNA Refseq: NM_003167
• Protein Refseq: NP_003158
• MIM: 125263
• UniProt ID: Q06520