Active Recombinant Human SULT2A1, His-tagged

• Cat.No.: SULT2A1-3545H
• Product Overview: Recombinant Human SULT2A1 fused with an N-terminal Met and 6-His tag, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.
• Source: E. coli
• Species: Human
• Tag: His
• Predicted N Terminal: Met
• Formulation: Supplied as a 0.2 µm filtered solution in Tris, NaCl and EDTA.
• Bio-activity: Measured by its ability to transfer sulfate from PAPS to t-Dehydroandrosterone (DHEA). The specific activity is >15 pmol/min/µg.
• Molecular Mass: Predicted Molecular Mass:35 kDa SDS-PAGE:36 kDa, reducing conditions
• Endotoxin: < 1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.

Gene Information

• Gene Name: SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 [ Homo sapiens (human) ]
• Official Symbol: SULT2A1
• Synonyms: SULT2A1; HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; bile salt sulfotransferase; bile-salt sulfotranasferase 2A1; alcohol/hydroxysteroid sulfotransferase; EC 2.8.2.14
• Gene ID: 6822
• mRNA Refseq: NM_003167
• Protein Refseq: NP_003158
• MIM: 125263
• UniProt ID: Q06520
• Chromosome Location: 19q13.3
• Pathway: Bile secretion; Biological oxidations; Chemical carcinogenesis
• Function: bile-salt sulfotransferase activity; protein binding; sulfotransferase activity