Recombinant Human STX1A
Cat.No. : | STX1A-214H |
Product Overview : | Recombinant syntaxin 1A protein(1-226aa) contains N-terminal domain(Habc) and t_SNARE domain(H3 domain) and this protein was overexpressed in E.coli and purified by using the conventional column chromatography techniques. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | Non |
Protein Length : | 1-226 a.a. |
Description : | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Form : | In 20mM Tris (pH 7.5), 1mM DTT, 10% glycerol |
Molecular Mass : | 26.1 kDa (226 aa), confirmed by MALDI-TOF. |
AA Sequence : | MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQ |
Purity : | > 95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name | STX1A syntaxin 1A (brain) [ Homo sapiens (human) ] |
Official Symbol | STX1A |
Synonyms | STX1A; syntaxin 1A (brain); STX1; HPC-1; p35-1; STX1A; Syntaxin-1A; Neuron-specific antigen HPC-1 |
Gene ID | 6804 |
mRNA Refseq | NM_004603 |
Protein Refseq | NP_004594 |
MIM | 186590 |
UniProt ID | Q16623 |
Chromosome Location | 7q11.23 |
Pathway | Acetylcholine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; GABA synthesis, release, reuptake and degradation |
Function | ATP-dependent protein binding; SNAP receptor activity; calcium channel inhibitor activity |
◆ Recombinant Proteins | ||
STX1A-5470R | Recombinant Rat STX1A Protein, His (Fc)-Avi-tagged | +Inquiry |
STX1A-13H | Recombinant Human Syntaxin 1A protein, 1-265aa | +Inquiry |
STX1A-214H | Recombinant Human STX1A | +Inquiry |
STX1A-6375H | Recombinant Human STX1A Protein, His-tagged | +Inquiry |
STX1A-4546R | Recombinant Rhesus monkey STX1A Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
STX1A-1717HCL | Recombinant Human STX1A cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All STX1A Products
Required fields are marked with *
My Review for All STX1A Products
Required fields are marked with *
0
Inquiry Basket