STX1A
-
Official Full Name
syntaxin 1A (brain) -
Overview
plays a role in neurotransmitter release [RGD, Feb 2006] -
Synonyms
STX1A;syntaxin 1A (brain);syntaxin-1A;P35A;syntaxin 1A (brain)-like;neuron-specific antigen HPC-1;synaptotagmin-associated 35 kDa protein
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Bovine
- Mus musculus
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- T7
- DDK
- Myc
- Avi
- Fc
Involved Pathway
STX1A involved in several pathways and played different roles in them. We selected most pathways STX1A participated on our site, such as SNARE interactions in vesicular transport,Synaptic vesicle cycle,Insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin secretion | CREB3L2,PLCB2,VAMP2,SLC2A2,GPR119,CAMK2G,RYR2,PRKACA,ATP1B1,ADCYAP1 |
| Synaptic vesicle cycle | ATP6V1C2,SLC17A8,ATP6V1F,ATP6V1G1,ATP6V0D1,CPLX4,ATP6V0A1,SLC18A2,SLC18A1,CPLX3 |
| SNARE interactions in vesicular transport | STX4,VTI1B,STX4A,VTI1A,STX18,BET1L,GS15,STX3A,STX8,STX10 |
Protein Function
STX1A has several biochemical functions, for example, ATP-dependent protein binding,SNAP receptor activity,SNARE binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX1A itself. We selected most functions STX1A had, and list some proteins which have the same functions with STX1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent protein binding | DNAJC5,DDX39B,SAE1,PRNP,MYO5A |
| SNAP receptor activity | STX3A,STX11,SYBL1,STX5AL,STX18,SNAP23.1,STX3,STX11B.1,STX7,VAMP8 |
| chloride channel inhibitor activity | STX7,STX8,WNK1,VTI1B,CFTR,VAMP8 |
| protein N-terminus binding | PARP1,STX5,SNCA,PDLIM5,NIPBL,EIF3E,SMARCE1,TGFB1,EXOC4,ERCC3 |
| SNARE binding | ANKRD27,SYBL1,STX4,VTI1B,VAMP5,STXBP1,STX7,EXOC3L4,GOSR1,STX2A |
| calcium channel inhibitor activity | TNNI3,SLC30A1A,FKBP1AB,ITPR1,FKBP1AA,PHPT1,SLC30A1B,CCDC109B,FKBP1B,PACSIN3 |
| protein binding, bridging | TJP2,TRIM5,TIRAP,RBM14,ANK2,IVL,FSCN1A,EVPL,MMS19,ADAP2 |
| glycoprotein binding | APOH,LGALS1,ITGB2,TFRC,EDEM2,FBXO17,ERLEC1,CSNK1D,LDLR,ACE2 |
| protein domain specific binding | TNFAIP1,COX4I2,MLF1,PLG,HOMER3,CACNB2,NFASC,ETV6,WNT3,WNT5A |
Interacting Protein
STX1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX1A here. Most of them are supplied by our site. Hope this information will be useful for your research of STX1A.
MDM2;SNAP23;TRDMT1;SNAP29;VIM;SNAP25;CCSER2;HTT
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References
- Russo, LM; Melton-Celsa, AR; et al. Comparisons of Native Shiga Toxins (Stxs) Type 1 and 2 with Chimeric Toxins Indicate that the Source of the Binding Subunit Dictates Degree of Toxicity. PLOS ONE 9:-(2014).
- Russo, LM; Melton-Celsa, AR; et al. Oral Intoxication of Mice with Shiga Toxin Type 2a (Stx2a) and Protection by Anti-Stx2a Monoclonal Antibody 11E10. INFECTION AND IMMUNITY 82:1213-1221(2014).
