Recombinant Human STX1A Protein, MYC/DDK-tagged

Cat.No. : STX1A-2988H
Product Overview : Recombinant Human STX1A protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Species : Human
Source : HEK293
Tag : DDK&Myc
Description : This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 28.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name STX1A syntaxin 1A (brain) [ Homo sapiens ]
Official Symbol STX1A
Synonyms HPC-1; P35-1; STX1; SYN1A
Gene ID 6804
mRNA Refseq NM_001165903
Protein Refseq NP_001159375
MIM 186590
UniProt ID Q16623

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