Recombinant Human STAT6 protein, His/MBP-tagged

• Cat.No.: STAT6-344H
• Product Overview: Recombinant Human STAT6(9-267 aa) fused with His/MBP tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants
• Source: E. coli
• Species: Human
• Tag: His&MBP
• Form: Liquid in PBS
• Protein length: 9-267 aa
• Purity: SDS-PAGE >90%
• Applications: WB Positive Control
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ]
• Official Symbol: STAT6
• Synonyms: STAT6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and activator of transcription 6; D12S1644; IL 4 STAT; STAT, interleukin4-induced; transcription factor IL-4 STAT; STAT6B; STAT6C; IL-4-STAT
• Gene ID: 6778
• mRNA Refseq: NM_001178078
• Protein Refseq: NP_001171549
• MIM: 601512
• UniProt ID: P42226