Recombinant Human SRGAP3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SRGAP3-970H
• Product Overview: SRGAP3 MS Standard C13 and N15-labeled recombinant protein (NP_055665) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: SRGAP3 (SLIT-ROBO Rho GTPase Activating Protein 3) is a Protein Coding gene. Diseases associated with SRGAP3 include Pilomyxoid Astrocytoma and Chromosome 3Pter-P25 Deletion Syndrome. Among its related pathways are Guidance Cues and Growth Cone Motility and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and Rac GTPase binding. An important paralog of this gene is SRGAP1.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 124.3 kDa
• AA Sequence: MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIELEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIFMNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESKLKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKARNDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLDVIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYHQLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYMSKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLSVYSHKLFNGSMEAFIKDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEVEQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMDDAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIPRRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSINYPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTVKQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALSARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTMTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Homo sapiens (human) ]
• Official Symbol: SRGAP3
• Synonyms: SRGAP3; SLIT-ROBO Rho GTPase activating protein 3; SLIT ROBO Rho GTPase activating protein 2, SRGAP2; SLIT-ROBO Rho GTPase-activating protein 3; ARHGAP14; KIAA0411; MEGAP; WRP; mental disorder-associated GAP; rho GTPase-activating protein 14; SLIT-ROBO Rho GTPase activating protein 2; WAVE-associated Rac GTPase activating protein; WAVE-associated Rac GTPase-activating protein; SRGAP2
• Gene ID: 9901
• mRNA Refseq: NM_014850
• Protein Refseq: NP_055665
• MIM: 606525
• UniProt ID: O43295