Recombinant Human SPINT2, His-tagged

• Cat.No.: SPINT2-91H
• Product Overview: Recombinant human SPINT2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: SPINT2, also known as kunitz-type protease inhibitor 2, inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This protein has been identified as a putative tumor suppressor gene silenced by promoter methylation.
• Form: Liquid. In phosphate buffered saline (pH 7.4), 10% glycerol.
• Molecular Mass: 20kDa (176aa) 18-28KDa (SDS-PAGE under reducing conditions.)
• AA Sequence: ADRERSIHDF CLVSKVVGRC RASMPRWWYN VTDGSCQLFV YGGCDGNSNN YLTKEECLKK CATVTENATG DLATSRNAAD SSVPSAPRRQ DSEDHSSDMF NYEEYCTANA VTGPCRASFP RWYFDVERNS CNNFIYGGCR GNKNSYRSEE ACMLRCFRQQ ENPPLPLGSK HHHHHH
• Endotoxin: < 1.0 eu per 1 microgram of protein (determined by lal
• Purity: >80% by SDS - PAGE.
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.2mg/ml (determined by absorbance at 280nm)

Gene Information

• Gene Name: SPINT2 serine peptidase inhibitor, Kunitz type, 2 [ Homo sapiens ]
• Official Symbol: SPINT2
• Synonyms: SPINT2; serine peptidase inhibitor, Kunitz type, 2; serine protease inhibitor, Kunitz type, 2; kunitz-type protease inhibitor 2; HAI 2; Kop; placental bikunin; hepatocyte growth factor activator inhibitor type 2; PB; HAI2; DIAR3; HAI-2; FLJ45571
• Gene ID: 10653
• mRNA Refseq: NM_001166103
• Protein Refseq: NP_001159575
• MIM: 605124
• UniProt ID: O43291
• Chromosome Location: 19q13.2
• Function: endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity