Recombinant Human SPI1 protein, His-tagged

• Cat.No.: SPI1-172H
• Product Overview: Recombinant Human SPI1, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 31 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Publications:
  Open chromatin profiling in adipose tissue marks genomic regions with functional roles in cardiometabolic traits (2019)

Gene Information

• Gene Name: SPI1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 [ Homo sapiens ]
• Official Symbol: SPI1
• Synonyms: SPI1; spleen focus forming virus (SFFV) proviral integration oncogene spi1; transcription factor PU.1; 31 kDa transforming protein; hematopoietic transcription factor PU.1; OF; PU.1; SFPI1; SPI 1; SPI 1 proto oncogene; SPI A; SPI-1 proto-oncogene; 31 kDa-transforming protein; SPI-1; SPI-A
• Gene ID: 6688
• mRNA Refseq: NM_001080547
• Protein Refseq: NP_001074016
• MIM: 165170
• UniProt ID: P17947