Recombinant Human SOX9

• Cat.No.: SOX9-30696TH
• Product Overview: Recombinant fragment, corresponding to amino acids 1-150 of Human SOX9 with proprietary tag, 150 amino acids, 43kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-150 a.a.
• Description: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Gene Information

• Gene Name: SOX9 SRY (sex determining region Y)-box 9 [ Homo sapiens ]
• Official Symbol: SOX9
• Synonyms: SOX9; SRY (sex determining region Y)-box 9; campomelic dysplasia, autosomal sex reversal , CMD1, CMPD1; transcription factor SOX-9; SRA1
• Gene ID: 6662
• mRNA Refseq: NM_000346
• Protein Refseq: NP_000337
• MIM: 608160
• Uniprot ID: P48436
• Chromosome Location: 17q23
• Pathway: Endochondral Ossification, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem
• Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enhancer bi