SOX9

  • Product List
  • Overview
  • Review / Q&A

  • Official Full Name

    SRY (sex determining region Y)-box 9

  • Overview

    The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]

  • Synonyms

    SOX9;SRY (sex determining region Y)-box 9;CMD1;SRA1;CMPD1;transcription factor SOX-9;SRY-related HMG-box, gene 9;SRY (sex-determining region Y)-box 9 protein

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • Yeast
  • In Vitro Cell Free System
  • GST
  • Non
  • His
  • Flag
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SOX9-2415H Recombinant Human SOX9, GST-tagged E.coli Human GST 316-510 a.a.
SOX9-30694TH Recombinant Human SOX9 E.coli Human Non 150 amino acids
SOX9-30695TH Recombinant Human SOX9 E.coli Human Non 194 amino acids
SOX9-30696TH Recombinant Human SOX9 E.coli Human Non 1-150 a.a.
SOX9-4416R Recombinant Rhesus monkey SOX9 Protein, His-tagged Mammalian Cells Rhesus macaque His
SOX9-5854C Recombinant Chicken SOX9 Mammalian Cells Chicken His
SOX9-1555HCL Recombinant Human SOX9 293 Cell Lysate HEK293 Human Non
SOX9-175HFL Active Recombinant Full Length Human SOX9 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
SOX9-2078H Recombinant Human SOX9 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
SOX9-2078H-B Recombinant Human SOX9 Protein Pre-coupled Magnetic Beads HEK293 Human
SOX9-2773H Recombinant Human SOX9 protein(101-270 aa), C-His-tagged E.coli Human His 101-270 aa
SOX9-3043H Recombinant Human SOX9 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
SOX9-3044H Recombinant Human SOX9 Protein, GST-tagged Wheat Germ Human GST
SOX9-3045H Recombinant Human SOX9 Protein, GST-tagged Wheat Germ Human GST
SOX9-360H Recombinant Human SOX9 Protein, His-GST-tagged E.coli Human GST&His Met1~Lys151
SOX9-4232R Recombinant Rhesus Macaque SOX9 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SOX9-4232R-B Recombinant Rhesus Macaque SOX9 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SOX9-5432H Recombinant Human SOX9 protein(1-509aa), His-tagged Yeast Human His 1-509aa
Sox9-6060M Recombinant Mouse Sox9 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
SOX9-6261HF Recombinant Full Length Human SOX9 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 509 amino acids
SOX9-6338H Recombinant Human SOX9 Protein (Met1-Lys151), N-His tagged E.coli Human His Met1-Lys151

Involved Pathway

SOX9 involved in several pathways and played different roles in them. We selected most pathways SOX9 participated on our site, such as cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cAMP signaling pathway GRIN2A,PDE4A,PDE4D,RELA,NPY,AKT2,GLI3,MAPK1,NFKB1,GRIN2B

Protein Function

SOX9 has several biochemical functions, for example, bHLH transcription factor binding,beta-catenin binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX9 itself. We selected most functions SOX9 had, and list some proteins which have the same functions with SOX9. You can find most of the proteins on our site.

Function Related Protein
chromatin binding ENY2,COQ7,NEUROD1,CENPB,DNMT3A,NR5A1,SMARCC1,MBD1,PARP1,BAZ1B
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding TFAM,ZFP750,PATZ1,MAFA,ATF4,FOSL1,FOXL2,CEBPB,NKX2-5,KLF15
protein binding STXBP1,NGDN,APPL2,SNAPC3,GTPBP4,SLAMF6,USH1G,SMARCAL1,LIPE,THRAA
pre-mRNA intronic binding RBM41,PRPF8,HNRNPA2B1,EP300,RNPC3,RBM4
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding USF1,GATA5,MYOG,NKX2-1,POU3F3,NR5A1,SRF,MEIS1,MYF5,RELA
transcription factor activity, sequence-specific DNA binding ZBTB14,ETV5A,HLF,NFE2L1,HIC1,HOXD10,STAT4,CITED2,CSRNP2,ZNF232
enhancer sequence-specific DNA binding LMO4,TFAP2B,KLF7B,TBX19,YY1,GATA5,TWIST1B,GATA4,SOX11,HMGB2
protein kinase activity PDK3,ROCK2B,LMTK2,RPS6KAL,CSNK1E,NEK10,MAPK12B,TLK1A,PRKACAA,KSR1
protein kinase A catalytic subunit binding PRKAR2B,CSK,PJA2,EZR,RYR2,PKIA,PRKAR2A,PRKAR1B,PRKAR1A,GSK3A

Interacting Protein

SOX9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX9.

ATP6V1H;dsdna_dadt:dadt

Resources

Research Area

Pancreatic Progenitor Cell Transcription Factors
Chondrogenesis Markers
Cancer Stem Cell Transcription Factors
Epithelial Stem Cell Transcription Factors
Hepatic and Pancreatic Progenitor Cell Transcription Factors
Mesenchymal Stem Cell Transcription Factors
Neural Stem Cell Transcription Factors
Intestinal Stem Cell Markers
Neural Stem Cell Markers

References

Reviews

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Q&As

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