Recombinant Human SOD2

• Cat.No.: SOD2-1039H

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. This protein transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain, into hydrogen peroxide and diatomic oxygen. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Research topic: Energy metabolism and body weight regulation
• Storage: Superoxide dismutase 2 is supplied with a vial of storage buffer (20 mM Tris, pH7.5). Store at -80°C.

Gene Information

• Gene Name: SOD2 superoxide dismutase 2, mitochondrial [ Homo sapiens ]
• Official Symbol: SOD2
• Synonyms: SOD2; superoxide dismutase 2, mitochondrial; IPOB; MNSOD; MVCD6; superoxide dismutase [Mn], mitochondrial; OTTHUMP00000017530; OTTHUMP00000017531; OTTHUMP00000238884; OTTHUMP00000238886; OTTHUMP00000238887; indophenoloxidase B; Mn superoxide dismutase; mangano-superoxide dismutase; manganese-containing superoxide dismutase
• Gene ID: 6648
• mRNA Refseq: NM_000636
• Protein Refseq: NP_000627
• MIM: 147460
• UniProt ID: P04179
• Chromosome Location: 6q25
• Pathway: FoxO family signaling; Huntington"s disease; Oxidative Stress; Peroxisome; Selenium Pathway
• Function: DNA binding; identical protein binding; manganese ion binding; manganese ion binding; oxidoreductase activity; oxygen binding; protein binding; superoxide dismutase activity