Recombinant Human SNRPB2, His-tagged

• Cat.No.: SNRPB2-3522H
• Product Overview: Recombinant human SNRPB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-225aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: SNRPB2, also known as U2 small nuclear ribonucleoprotein B, belongs to the RRM U1 A/B family. This protein associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A. It may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl
• Molecular Weight: 27.6 kDa (245aa), confirmed by MALDI-TOF
• Purity: >90% by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradfordassay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MDIRPNHTIY INNMNDKIKK EELKRSLYAL FSQFGHVVDI VALKTMKMRG QAFVIFKELG SSTNALRQLQ GFPFYGKPMR IQYAKTDSDI ISKMRGTFAD KEKKKEKKKA KTVEQTATTT NKKPGQGTPN SANTQGNSTP NPQVPDYPPN YILFLNNLPE ETNEMMLSML FNQFPGFKEV RLVPGRHDIA FVEFENDGQA GAARDALQGF KITPSHAMKITYAKK
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SNRPB2 small nuclear ribonucleoprotein polypeptide B [ Homo sapiens ]
• Synonyms: SNRPB2; Msl1; MGC24807; MGC45309; U2 small nuclear ribonucleoprotein B"; U2 snRNP B"; small nuclear ribonucleoprotein polypeptide B2
• Gene ID: 6629
• mRNA Refseq: NM_003092
• Protein Refseq: NP_003083
• MIM: 603520
• UniProt ID: P08579
• Chromosome Location: 20p12.1
• Function: RNA binding; nucleotide binding; protein binding