Recombinant Human SNRPA protein, His-tagged

• Cat.No.: SNRPA-493H
• Product Overview: Recombinant Human SNRPA(8-278 aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 8-278 a.a.
• Description: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
• AA Sequence: PNHTIYINNL NEKIKKDELK KSLYAIFSQF GQILDILVSR SLKMRGQAFV IFKEVSSATN ALRSMQGFPF YDKPMRIQYA KTDSDIIAKM KGTFVERDRK REKRKPKSQE TPATKKAVQG GGATPVVGAV QGPVPGMPPM TQAPRIMHHM PGQPPYMPPP GMIPPPGLAP GQIPPGAMPP QQLMPGQMPP AQPLSENPPN HILFLTNLPE ETNELMLSML FNQFPGFKEV RLVPGRHDIA FVEFDNEVQA GAARD
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.

Gene Information

• Gene Name: SNRPA small nuclear ribonucleoprotein polypeptide A [ Homo sapiens ]
• Official Symbol: SNRPA
• Synonyms: SNRPA; small nuclear ribonucleoprotein polypeptide A; U1 small nuclear ribonucleoprotein A; Mud1; U1 A; U1A; U1 snRNP A; U1 snRNP-specific protein A; U1 small nuclear RNP-specific A; U1-A
• Gene ID: 6626
• mRNA Refseq: NM_004596
• Protein Refseq: NP_004587
• MIM: 182285
• UniProt ID: P09012
• Chromosome Location: 19q13.1
• Pathway: Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; Spliceosome, U1-snRNP, organism-specific biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem
• Function: RNA binding; nucleotide binding; protein binding; snRNA binding