Recombinant Human SNAP25 Protein, His-tagged

• Cat.No.: SNAP25-297H
• Product Overview: Recombinant Human SNAP25 protein, fused with His-tag, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-197 aa
• Description: Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
• Form: 50mM HEPES buffer (pH 7.4) containing 5mM DTT, 100mM NaCl.
• Molecular Mass: 24.6 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQ
• Purity: >90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.14 mg/ml

Gene Information

• Gene Name: SNAP25 synaptosome associated protein 25 [ Homo sapiens (human) ]
• Official Symbol: SNAP25
• Synonyms: SUP; RIC4; SEC9; SNAP; CMS18; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2
• Gene ID: 6616
• mRNA Refseq: NM_130811.4
• Protein Refseq: NP_570824.1
• MIM: 600322
• UniProt ID: P60880