SNAP25
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Official Full Name
epidermal transglutaminase -
Overview
A transglutaminase is an enzyme that catalyzes the formation of a covalent bond between a free amine group (e.g., protein- or peptide-bound lysine) and the gamma-carboxamide group of protein- or peptide-bound glutamine. Such an enzyme is classified as EC 2.3.2.13. Bonds formed by transglutaminase exhibit high resistance to proteolytic degradation (proteolysis). -
Synonyms
eTG;epidermal transglutaminase
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- E. coli
- HEK293T
- His
- Non
- His&Strep
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SNAP25 involved in several pathways and played different roles in them. We selected most pathways SNAP25 participated on our site, such as Synaptic vesicle cycle,Insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAP25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Insulin secretion | STX1A,PLCB2,PRKACA,SLC2A1,PRKACG,PLCB1,ITPR3,RAB3A,GNA11,RIMS2 |
Synaptic vesicle cycle | STX2,SLC17A6,ATP6V0D1,ATP6V0E2,ATP6V0B,SLC18A2,ATP6V1B2,ATP6V1G1,ATP6V1A,ATP6V1E1 |
Protein Function
SNAP25 has several biochemical functions, for example, SNAP receptor activity,calcium-dependent protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAP25 itself. We selected most functions SNAP25 had, and list some proteins which have the same functions with SNAP25. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
calcium-dependent protein binding | CASQ2,S100PBP,VAMP2,CHP1,STX1A,MBL2,CPNE3,ALG2,NRXN1,VPS37B |
protein binding | CINP,ABT1,SH3GL1,MAL,BIK,PRKCB,EFNB1,KIAA1737,C9orf9,TIPRL |
SNAP receptor activity | STX7,STX3,SEC22A,STX3A,SNAP23.1,STX2,VAMP2,VTI1B,SEC22BB,STX16 |
syntaxin-1 binding | VAMP3,DAPK1,CPLX1,SNPH,VAMP2,UNC13A,SYT1,STXBP3A,SNAP25A,RNF40 |
Interacting Protein
SNAP25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAP25 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAP25.
STX11;ZDHHC17;CCDC53;Cplx1;EGFR;STX1A;PRRT2;SNAPIN;HTT;ITSN1;Slc14a2;ITSN1
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References
- Wang, DX; Krilich, J; et al. Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay. ANALYTICAL BIOCHEMISTRY 468:15-21(2015).
- Hao, JX; Chen, M; et al. Equatorin is not essential for acrosome biogenesis but is required for the acrosome reaction. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 444:537-542(2014).