Recombinant Human SMARCC2

• Cat.No.: SMARCC2-31424TH
• Product Overview: Recombinant full length Human SMRC2 isoform 2 with a N terminal proprietary tag; Predicted MWt 150.30 kDa.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 1130 amino acids
• Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Molecular Weight: 150.300kDa inclusive of tags
• Tissue specificity: Ubiquitously expressed.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQ AEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKC FLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDII KRHQGTVTEDKNNASHVVYPVPGNLEEEEWVRPVMKRDKQ VLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDE VNSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGP STPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENST GNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHA IERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRP TPMGPPPTSHFHVLADTPSGLVPLQPKTPQGRQVDADTKA GRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLL LEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYL EDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKA DPAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEK KEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKV ERDIGEGNLSTAAAAALAAAAVKAKHFAAVEERKIKSLVA LLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGS QPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGP SEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS PFPNQQTPPSMMPGAVPGSGHPGVADPGTPLPPDPTAPSP GTVTPVPPPQ
• Sequence Similarities: Belongs to the SMARCC family.Contains 1 SANT domain.Contains 1 SWIRM domain.

Gene Information

• Gene Name: SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 [ Homo sapiens ]
• Official Symbol: SMARCC2
• Synonyms: SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF complex subunit SMARCC2; BAF170; CRACC2; Rsc8
• Gene ID: 6601
• mRNA Refseq: NM_139067
• Protein Refseq: NP_620706
• MIM: 601734
• Uniprot ID: Q8TAQ2
• Chromosome Location: 12q13.2
• Pathway: Glucocorticoid receptor regulatory network, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: DNA binding; protein binding; transcription coactivator activity