Recombinant Human SMARCB1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SMARCB1-6177H
• Product Overview: SMARCB1 MS Standard C13 and N15-labeled recombinant protein (NP_001007469) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 43.2 kDa
• AA Sequence: MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAWTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [ Homo sapiens (human) ]
• Official Symbol: SMARCB1
• Synonyms: SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SNF5L1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BAF47; hSNFS; Ini1; integrase interactor 1; malignant rhabdoid tumor suppressor; RDT; Sfh1p; Snr1; sucrose nonfermenting; yeast; homolog like 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; sucrose nonfermenting, yeast, homolog-like 1; INI1; SNF5; RTPS1
• Gene ID: 6598
• mRNA Refseq: NM_001007468
• Protein Refseq: NP_001007469
• MIM: 601607
• UniProt ID: Q12824