Recombinant Human SMARCB1 cell lysate

• Cat.No.: SMARCB1-1647HCL

Specification

• Description: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot
• Tag: Non

Gene Information

• Gene Name: SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [ Homo sapiens ]
• Official Symbol: SMARCB1
• Synonyms: SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SNF5L1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BAF47; hSNFS; Ini1; integrase interactor 1; malignant rhabdoid tumor suppressor; RDT; Sfh1p; Snr1; sucrose nonfermenting; yeast; homolog like 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; sucrose nonfermenting, yeast, homolog-like 1; INI1; SNF5; RTPS1
• Gene ID: 6598
• mRNA Refseq: NM_001007468
• Protein Refseq: NP_001007469
• MIM: 601607
• UniProt ID: Q12824
• Chromosome Location: 22q11.23
• Pathway: Regulation of retinoblastoma protein, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: Tat protein binding; p53 binding; protein binding; transcription coactivator activity; transcription coactivator activity