Recombinant Human SMARCAL1 Protein, His-tagged

• Cat.No.: SMARCAL1-23H
• Product Overview: Recombinant protein of Human SMARCAL1, transcript variant 1, full length, with N-terminal His tag, was expressed in E. coli

Specification

• Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 106.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 50mM Tris, pH8.0, 8M Urea.

Gene Information

• Gene Name: SMARCAL1
• Official Symbol: SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 [ Homo sapiens (human) ]
• Synonyms: SMARCAL1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; HARP; HHARP
• Gene ID: 50485
• mRNA Refseq: NM_014140
• Protein Refseq: NP_054859
• MIM: 606622
• UniProt ID: Q9NZC9