Recombinant Human SMARCAL1 Protein, GST-tagged

• Cat.No.: SMARCAL1-22H
• Product Overview: Human SMARCAL1 full-length ORF ( NP_054859.2, 1 a.a. - 954 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 132.3 kDa
• AA Sequence: MSLPLTEEQRKKIEENRQKALARRA EKLLAEQHQRTSSGTSIAGNPFQAK QGPSQNFPRESCKPVSHGVIFKQQN LSSSSNADQRPHDSHSFQAKGIWKK PEEMPTACPGHSPRSQMALTGISPP LAQSPPEVPKQQLLSYELGQGHAQA SPEIRFTPFANPTHKPLAKPKSSQE TPAHSSGQPPRDAKLEAKTAKASPS GQNISYIHSSSESVTPRTEGRLQQK SGSSVQKGVNSQKGKCVRNGDRFQV LIGYNAELIAVFKTLPSKNYDPDTK TWNFSMNDYSALMKAAQSLPTVNLQ PLEWAYGSSESPSTSSEGQAGLPSA PSLSFVKGRCMLISRAYFEADISYS QDLIALFKQMDSRRYDVKTRKWSFL LEEHSKLIAKVRCLPQVQLDPLPTT LTLAFASQLKKTSLSLTPDVPEADL SEVDPKLVSNLMPFQRAGVNFAIAK GGRLLLADDMGLGKTIQAICIAAFY RKEWPLLVVVPSSVRFTWEQAFLRW LPSLSPDCINVVVTGKDRLTAGLIN IVSFDLLSKLEKQLKTPFKVVIIDE SHFLKNSRTARCRAAMPVLKVAKRV ILLSGTPAMSRPAELYTQIIAVKPT FFPQFHAFGLRYCDAKRMPWGWDYS GSSNLGELKLLLEEAVMLRRLKSDV LSQLPAKQRKIVVIAPGRINARTRA ALDAAAKEMTTKDKTKQQQKDALIL FFNRTAEAKIPSVIEYILDLLESGR EKFLVFAHHKVVLDAITQELERKHV QHIRIDGSTSSAEREDLCQQFQLSE RHAVAVLSITAANMGLTFSSADLVV FAELFWNPGVLIQAEDRVHRIGQTS SVGIHYLVAKGTADDYLWPLIQEKI KVLAEAGLSETNFSEMTESTDYLYK DPKQQKIYDLFQKSFEKEGSDMELL EAAESFDPGSASGTSGSSSQNMGDT LDESSLTASPQKKRRFEFFDNWDSF TSPL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: SMARCAL1
• Official Symbol: SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 [ Homo sapiens (human) ]
• Synonyms: SMARCAL1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; HARP; HHARP
• Gene ID: 50485
• mRNA Refseq: NM_014140
• Protein Refseq: NP_054859
• MIM: 606622
• UniProt ID: Q9NZC9