Recombinant Human SLC11A1 Protein (T2-G550), 8×His-MBP, Flag tagged

• Cat.No.: SLC11A1-0391H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC11A1(T2-G550)-Flag Protein was expressed in Insect cell.

Specification

• Description: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
• Source: Insect cell
• Species: Human
• Tag: His&Flag&MBP
• Form: Liquid
• Protein length: T2-G550
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 [ Homo sapiens (human) ]
• Official Symbol: SLC11A1
• Synonyms: SLC11A1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1; LSH, NRAMP, NRAMP1; natural resistance-associated macrophage protein 1; natural resistance associated macrophage protein 1; NRAMP 1; solute carrier family 11 (sodium/phosphate symporters), member 1; LSH; NRAMP; NRAMP1
• Gene ID: 6556
• mRNA Refseq: NM_000578
• Protein Refseq: NP_000569
• MIM: 600266
• UniProt ID: P49279