Recombinant Human SIRT5
Cat.No. : | SIRT5-342H |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | Sirtuins are pylogenetically conserved from bacteria to humans and regulate cell functions beyond silencing. The proteins show a relevance to cancer, obesity, muscle differentiation, inflammation and neuro-degeneration. In addition, Sirtuin activity may extend the lifespan of several organisms. Human Sirtuin 5 (Sirt5) is a mitochondrial member of Class III of the protein deacetylases family (historically called histone deacetylases family). Class III deacetylases utilize NAD+ as cosubstrate and act either as deacetylases or as ADP-ribosyltransferases. MW=29.9kDa (275 amino acids). |
Form : | Purified recombinant protein in 20mM Tris-HCl pH7.8, 150mM NaCl and 2mM DTT. |
Purity : | >95% by SDS-PAGE. |
Usage : | For in vitro use only. |
Storage : | Quality guaranteed for 12 months store at -80℃. Avoid freeze / thaw cycles. |
Gene Name | SIRT5 sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) [ Homo sapiens ] |
Synonyms | SIRT5; sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae); SIR2L5; FLJ36950; sirtuin 5; sir2-like 5; sirtuin type 5; silent mating type information regulation 2, S.cerevisiae, homolog 5; EC 3.5.1.-; OTTHUMP00000016054; OTTHUMP00000016055; SIR2-like protein 5; sirtuin (silent mating type information regulation; S.cerevisiae, homolog) 5 |
Gene ID | 23408 |
mRNA Refseq | NM_012241 |
Protein Refseq | NP_036373 |
MIM | 604483 |
UniProt ID | Q9NXA8 |
Chromosome Location | 6p23 |
Function | NAD binding; NAD+ ADP-ribosyltransferase activity; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; metal ion binding; zinc ion binding |
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◆ Cell & Tissue Lysates | ||
SIRT5-1830HCL | Recombinant Human SIRT5 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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