Recombinant Human SIRT5 Protein, GST-tagged

• Cat.No.: SIRT5-110H
• Product Overview: Recombinant N-terminal GST-tagged human SIRT5 protein was purified from E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
• Molecular Mass: 60.6 kDa
• Purity: ≥90% as determined by SDS-PAGE
• Applications: WB, ELISA
• Stability: ≥ 2 year
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM NaPO4, pH 7.2, 100 mM sodium chloride, 5mM DTT, 20% glycerol

Gene Information

• Gene Name: SIRT5 sirtuin 5 [ Homo sapiens (human) ]
• Official Symbol: SIRT5
• Synonyms: SIRT5; sirtuin 5; SIR2L5; NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent deacetylase sirtuin-5; NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial; silent mating type information regulation 2, S.cerevisiae, homolog 5; sir2-like 5; sirtuin type 5
• Gene ID: 23408
• mRNA Refseq: NM_031244
• Protein Refseq: NP_112534
• MIM: 604483
• UniProt ID: Q9NXA8