Recombinant Human SIRPB1 Protein, Isoform 3, Glu30-Leu371, C-His-Avi tagged, Biotinylated

• Cat.No.: SIRPB1-230H
• Product Overview: Recombinant human SIRP Beta 1 Isoform 3-C-His-Avi protein was developed from HEK293 and has a target region of C-His-Avi.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Glu30-Leu371
• Description: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM

Gene Information

• Gene Name: SIRPB1 signal-regulatory protein beta 1 [ Homo sapiens (human) ]
• Official Symbol: SIRPB1
• Synonyms: SIRPB1; signal-regulatory protein beta 1; signal-regulatory protein beta-1; CD172b; SIRP BETA 1; CD172 antigen-like family member B; SIRP-BETA-1; FLJ26614; DKFZp686A05192
• Gene ID: 10326
• mRNA Refseq: NM_001083910
• Protein Refseq: NP_001077379
• MIM: 603889
• UniProt ID: O00241