Recombinant Human SIRPB1 cell lysate

• Cat.No.: SIRPB1-1608HCL

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SIRPB1 signal-regulatory protein beta 1 [ Homo sapiens ]
• Official Symbol: SIRPB1
• Synonyms: SIRPB1; signal-regulatory protein beta 1; signal-regulatory protein beta-1; CD172b; SIRP BETA 1; CD172 antigen-like family member B; SIRP-BETA-1; FLJ26614; DKFZp686A05192
• Gene ID: 10326
• mRNA Refseq: NM_001083910
• Protein Refseq: NP_001077379
• MIM: 603889
• UniProt ID: O00241
• Chromosome Location: 20p13
• Pathway: Cell-Cell communication, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Signal regulatory protein (SIRP) family interactions, organism-specific biosystem
• Function: protein binding