Recombinant Human SHOX Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SHOX-5586H
• Product Overview: SHOX MS Standard C13 and N15-labeled recombinant protein (NP_000442) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene belongs to the paired homeobox family and is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. Defects in this gene are associated with idiopathic growth retardation and in the short stature phenotype of Turner syndrome patients. This gene is highly conserved across species from mammals to fish to flies. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Molecular Mass: 32.1 kDa
• AA Sequence: MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGLTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SHOX short stature homeobox [ Homo sapiens (human) ]
• Official Symbol: SHOX
• Synonyms: SHOX; short stature homeobox; short stature homeobox protein; GCFX; PHOG; SHOXY; SS; growth control factor, X-linked; short stature homeobox-containing protein; pseudoautosomal homeobox-containing osteogenic protein
• Gene ID: 6473
• mRNA Refseq: NM_000451
• Protein Refseq: NP_000442
• MIM: 312865
• UniProt ID: O15266