Recombinant Human SETD2 protein, GST-tagged

• Cat.No.: SETD2-260H
• Product Overview: Recombinant Human SETD2(1345-1711 aa) fused with GST tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1345-1711 a.a.
• Description: SETD2 is a SET-domain containing histone methyltransferase, catalyzing the trimethylation of histone H3 at lysine 36. SETD2 is a candidate tumor suppressor protein and mutated in clear cell renal cell carcinoma.
• Form: In 50mM Tris pH 7.3, 300 mM NaCl, 4mM DTT, 1µM ZnCl2 and 25% glycerol.
• Molecular Mass: 68 kDa
• Applications: SETD2, Recombinant Human GST-tagged is useful for histone H3 methylation experiments, enzyme kinetics and inhibitor screening. Use of 0.5 - 2.5 µg SETD2 per reaction with nucleosomes or recombinant histone H3 as a substrate is recommended.
• Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
• Concentration: 1 µg/µl

Gene Information

• Gene Name: SETD2 SET domain containing 2 [ Homo sapiens ]
• Official Symbol: SETD2
• Synonyms: SETD2; SET domain containing 2; histone-lysine N-methyltransferase SETD2; FLJ23184; HIF 1; HYPB; KIAA1732; KMT3A; huntingtin yeast partner B; lysine N-methyltransferase 3A; huntingtin interacting protein 1; huntingtin-interacting protein B; SET2; HIF-1; HIP-1; HBP231; HSPC069; p231HBP; FLJ16420; FLJ22472; FLJ45883; FLJ46217
• Gene ID: 29072
• mRNA Refseq: NM_014159
• Protein Refseq: NP_054878
• MIM: 612778
• UniProt ID: Q9BYW2
• Chromosome Location: 3p21.31
• Pathway: Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem