Recombinant Human Serine/Threonine Kinase 32B, GST-tagged

• Cat.No.: STK32B-1105H
• Product Overview: Full-length recombinant human STK32B (YANK2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: STK32B-1105H
• Description: STK32B or YANK2 is a serine/threonine protein kinase that contains motif for binding metal ions and nucleotides and the gene for STK32B is highly conserved among various species. STK32B has been associated with isolated cleft lip with or without cleft palate and cleft palate which are among the most common human birth defects of oral cleft cases. Long interspersed nuclear element-1 (LINE-1 or L1) mediated deletion of STK32B gene is observed in patients with Ellis-van Creveld syndrome with borderline intelligence.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 72 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
• Purity: > 95 %
• Specific Activity: 14 nmol/min/mg
• Concentration: 0.1 ug/ul
• Sequences: Full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: STK32B serine/threonine kinase 32B [ Homo sapiens ]
• Official Symbol: STK32B
• Synonyms: STK32B; serine/threonine kinase 32B; STK32; STKG6; YANK2; HSA250839; Serine/threonine kinase 32B; EC=2.7.11.1; gene for serine/threonine protein kinase; serine/threonine-protein kinase 32B; EC 2.7.11; EC 2.7.11.1; OTTHUMP00000217008; OTTHUMP00000217009; OTTHUMP00000217010; OTTHUMP00000115490
• Gene ID: 55351
• mRNA Refseq: NM_018481
• Protein Refseq: NP_060871
• UniProt ID: Q9NY57
• Chromosome Location: 4p16.2
• Function: ATP binding; metal ion binding; nucleotide binding; protein serine/threonine kinase activity