Active Recombinant Human STK32B, GST-tagged

• Cat.No.: STK32B-1487H
• Product Overview: Full-length recombinant human STK32B (YANK2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: STK32B or YANK2 is a serine/threonine protein kinase that contains motif for binding metal ions and nucleotides and the gene for STK32B is highly conserved among various species. STK32B has been associated with isolated cleft lip with or without cleft palate and cleft palate which are among the most common human birth defects of oral cleft cases. Long interspersed nuclear element-1 (LINE-1 or L1) mediated deletion of STK32B gene is observed in patients with Ellis-van Creveld syndrome with borderline intelligence.
• Source: Sf9 Cells
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 14 nmol/min/mg
• Molecular Mass: ~72 kDa
• Protein length: Full length
• Purity: >95%
• Applications: Kinase Assay, Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: STK32B serine/threonine kinase 32B [ Homo sapiens ]
• Official Symbol: STK32B
• Synonyms: STK32B; serine/threonine kinase 32B; serine/threonine-protein kinase 32B; HSA250839; STK32; STKG6; YANK2; gene for serine/threonine protein kinase
• Gene ID: 55351
• mRNA Refseq: NM_018401
• Protein Refseq: NP_060871
• UniProt ID: Q9NY57
• Chromosome Location: 4p16
• Function: ATP binding; metal ion binding; nucleotide binding; protein serine/threonine kinase activity