Recombinant Human Secretory Leukocyte Peptidase Inhibitor, His-tagged

• Cat.No.: SLPI-2575H
• Product Overview: Recombinant human SLPI, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography. MW = 14.0kDa (128aa).

Specification

• Cat. No.: SLPI-2575H
• Description: SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.
• Source: E.coli.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSGKSFKAGV CPPKKSAQCL RYKKPECQSD WQCPGKKRCC PDTCGIKCLD PVDTPNPTRR KPGKCPVTYG QCLMLNPPNF CEMDGQCKRD LKCCMGMCGK SCVSPVKA
• Purity: > 80% by SDS – PAGE.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SLPI secretory leukocyte peptidase inhibitor [ Homo sapiens ]
• Synonyms: SLPI; secretory leukocyte peptidase inhibitor; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; antileukoproteinase; HUSI-1; protease inhibitor WAP4; mucus proteinase inhibitor; seminal proteinase inhibitor; WAP four-disulfide core domain 4; WAP four-disulfide core domain protein 4; secretory leukocyte protease inhibitor (antileukoproteinase);Secretory leukocyte protease inhibitor
• Gene ID: 6590
• mRNA Refseq: NM_003064
• Protein Refseq: NP_003055
• MIM: 107285
• UniProt ID: P03973
• Chromosome Location: 20q12
• Function: endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity