Recombinant Human S100A12 protein, Myc/DDK-tagged

• Cat.No.: S100A12-33H
• Product Overview: Recombinant protein of human S100 calcium binding protein A12 (S100A12) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
• Molecular Mass: 10.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: S100A12 S100 calcium binding protein A12 [ Homo sapiens (human) ]
• Official Symbol: S100A12
• Synonyms: S100A12; S100 calcium binding protein A12; p6; CAGC; CGRP; MRP6; CAAF1; MRP-6; ENRAGE; protein S100-A12; EN-RAGE; calcitermin; calcium-binding protein in amniotic fluid 1; calgranulin C; extracellular newly identified RAGE-binding protein; migration inhibitory factor-related protein 6; neutrophil S100 protein
• Gene ID: 6283
• mRNA Refseq: NM_005621
• Protein Refseq: NP_005612
• MIM: 603112
• UniProt ID: P80511