Recombinant Human RUVBL2, GST tagged

• Cat.No.: RUVBL2-2475H
• Product Overview: Recombinant Human RUVBL2 full-length ORF ( AAH00428, 1 a.a. - 463 a.a.) was expressed in Wheat Germ with GST-tag at N-terminal.

Specification

• Description: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
• Source: Wheat Germ (in vitro)
• Species: Human
• Tag: GST
• Form: Liquid
• Molecular Mass: 76.67 kDa
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RUVBL2 RuvB-like 2 (E. coli) [ Homo sapiens ]
• Official Symbol: RUVBL2
• Synonyms: RUVBL2; RuvB-like 2 (E. coli); RuvB (E coli homolog) like 2; ruvB-like 2; ECP51; INO80 complex subunit J; INO80J; reptin; Reptin52; Rvb2; RVB2; TIH2; TIP48; TIP49b; ECP-51; reptin 52; TAP54-beta; reptin52 protein; repressing pontin 52; RuvB (E coli homolog)-like 2; 48 kDa TBP-interacting protein; TBP-interacting protein, 48-KD; TIP60-associated protein 54-beta; 51 kDa erythrocyte cytosolic protein; erythrocyte cytosolic protein, 51-KD; 48 kDa TATA box-binding protein-interacting protein; CGI-46; REPTIN; TIP49B
• Gene ID: 10856
• mRNA Refseq: NM_006666
• Protein Refseq: NP_006657
• MIM: 604788
• UniProt ID: Q9Y230
• Chromosome Location: 19q13.3
• Pathway: ATF-2 transcription factor network, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Extension of Telomeres, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Telomere Extension By Telomerase, organism-specific biosystem
• Function: ATP binding; ATP-dependent DNA helicase activity; contributes_to ATPase activity; DNA helicase activity; damaged DNA binding; hydrolase activity; identical protein binding; identical protein binding; nucleotide binding; protein binding; unfolded protein binding