Recombinant Human RUVBL1, His-tagged

Description :	RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with RUVBL2 protein.
Protein length :	456 amino acids
Conjugation :	HIS
Molecular Weight :	52.300kDa inclusive of tags
Source :	E. coli
Tissue specificity :	Ubiquitously expressed with high expression in heart, skeletal muscle and testis.
Form :	Liquid
Purity :	>95% by SDS-PAGE
Storage buffer :	Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0
Storage :	Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids :	MGSSHHHHHHSSGLVPRGSHMKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK
Sequence Similarities :	Belongs to the ruvB family.

Gene Name	RUVBL1 RuvB-like 1 (E. coli) [ Homo sapiens ]
Official Symbol	RUVBL1
Synonyms	RUVBL1; RuvB-like 1 (E. coli); RuvB (E coli homolog) like 1; ruvB-like 1; ECP54; INO80 complex subunit H; INO80H; NMP238; pontin; Pontin52; RVB1; Rvb1; TIH1; TIP49; TIP49a;
Gene ID	8607
mRNA Refseq	NM_003707
Protein Refseq	NP_003698
MIM	603449
Uniprot ID	Q9Y265
Chromosome Location	3q21
Pathway	C-MYC pathway, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Extension of Telomeres, organism-specific biosystem; Nucleosome assembly, organism-specific biosystem;
Function	ATP binding; NOT ATPase activity; DNA helicase activity; hydrolase activity; nucleotide binding;