RUVBL1
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Official Full Name
RuvB-like 1 -
Overview
RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with RUVBL2 protein. -
Synonyms
RUVBL1;RuvB-like 1 (E. coli);RuvB (E coli homolog) like 1;ruvB-like 1;ECP54;INO80 complex subunit H;INO80H;NMP238;pontin;Pontin52;RVB1;TIH1;TIP49;TIP49a;ECP-54;NMP 238;pontin 52;TAP54-alpha;nuclear matrix protein 238;RuvB (E coli
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- Insect Cells
- HEK293
- GST
- His
- Non
- DDK&Myc
- Avi&Fc&His
- Flag
Involved Pathway
RUVBL1 involved in several pathways and played different roles in them. We selected most pathways RUVBL1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RUVBL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | WNT2,FZD3A,NKD2B,NLK,TLE3A,MAPK8,CAMK2D1,FBXW11,CSNK1A1L,NKD2 |
Protein Function
RUVBL1 has several biochemical functions, for example, ATP binding,NOT ATPase activity,DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RUVBL1 itself. We selected most functions RUVBL1 had, and list some proteins which have the same functions with RUVBL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ULK1,RPS6KAL,TTLL11,NUAK2,CKMT1B,HSPD1,SGK3,PFKFB2,MYH8,MAPK8B |
| protein binding | PCDH18B,WDR11,FAM158A,PLEKHB2,DISC1,SLC6A3,SOD1,NDUFB10,SRRT,EXOSC1 |
| DNA helicase activity | PEO1,RAD54B,SUPV3L1,MCM3L,MCM6L,RECQL5,PIF1,RUVBL2,MCM5,CHD8 |
| NOT ATPase activity | KIF26A,CLU,MYO18A |
Interacting Protein
RUVBL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RUVBL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RUVBL1.
RUVBL2
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References
- Lacombe, J; Mange, A; et al. A Multiparametric Serum Marker Panel as a Complementary Test to Mammography for the Diagnosis of Node-Negative Early-Stage Breast Cancer and DCIS in Young Women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:1834-1842(2014).
- Kaji, K; Fertig, N; et al. Autoantibodies to RuvBL1 and RuvBL2: A Novel Systemic Sclerosis-Related Antibody Associated With Diffuse Cutaneous and Skeletal Muscle Involvement. ARTHRITIS CARE & RESEARCH 66:575-584(2014).
